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Pesticide Residue Induced Hepatotoxicity: Determination for Animal Studies Based on Fuzzy Logic |
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PP: 365-378 |
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doi:10.18576/amis/190212
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Author(s) |
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N. Yogeesh,
Suleiman Ibrahim Mohammad,
J. Divyashree,
N. Raja,
Asokan Vasudevan,
Hongli Long,
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Abstract |
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| Exposure to an excessive number of environmental stressors, such as pesticides, is regarded to be hazardous to health and a substantial contributor to the majority of public health diseases. Numerous physiological activities have been demonstrated to alter the pesticide’s hepatotoxicity. Hepatotoxicity is a term that refers to a pesticide’s intrinsic propensity to cause harm or death, demonstrating how deadly the chemical is. Hepatotoxicity leads to many diseases with preliminary examination shows inflammation in liver when pesticide residues more in the blood than the liver is able to manage. Pesticides such as Endosulfan, Phorate and Fenvalerate causes harmful effects in mammalian system. The liver of rats treated with Endosulfan exhibited leukocyte infiltration, activated Kupffer cells, sinusoidal dilation of the circulation. Phorate treated rats causes bile pigmentation and necrotic granulomas. Fenvalerate treated rats’ liver section shows hepatocellular necro inflammation and hepatocellur damage.
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