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Test of Significance of Spectrum Choice on the Dose Distribution of High Dose Rate Ir-192 Brachytherapy Source |
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PP: 307-310 |
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doi:10.18576/jrna/090313
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Author(s) |
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O. M. Oni,
O. O. Oloyede,
A. A. Aremu,
E. A. Oni,
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Abstract |
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| This study which follows test case 1 of the joint AAPM/ESTRO/ABG MBDCA-WG test cases investigates the impact of spectrum choice on the dose delivered by high dose rate (HDR) 192Ir brachytherapy source placed in a water phantom. Geant4 Application for Tomography Emission (GATE) Monte Carlo Simulation toolkit macro script was written to design the geometry, materials, physics, actors, and radiation source for the simulation. Embedded in the water phantom was the simulated Microselectron HDR 192Ir source. Five different spectra of the HDR192Ir were considered, each defined according to its energy and intensity level. The emstandard_opt4 was adopted for the physics of the simulation process, with DoseActor as the scoring medium.
The results of the simulation with 4 x108 run histories revealed that the absorbed varied significantly with spectrum choice. The dose was determined to range from 2.65 x 10-7 to 2.07 cGy for Shirley; 1.19 x 10-8 and 3.65 cGy for Amersham and 1.59 x 10-7 to 2.57 cGy for Glasgow and Dillman. The NNDC spectrum was between 6.82 x 10-8 to 2.00 cGy while dose value between 1.36 x 10-5 and 1.74 cGy was observed for Duchemin and Coursol. The pairwise comparison of the spectra at 95% confidence level showed that among the five spectra, the pair combinations of NNDC, Shirley and Duchemin and Coursol spectra only were found to have no significant difference with the absorbed dose. |
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