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Design of a Mathematical Computational Phantom for Oncopediatric Patients for the Pet/Ct Study |
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PP: 185-191 |
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Author(s) |
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Manuel I. León-Madrid,
Georgina C. Waldo,
Georgina C. Waldo,
Karen A. Castañeda,
Pablo V. Cerón,
Modesto A. Sosa,
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Abstract |
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| The main objective of this work was to design a mathematical computational phantom for on-pediatric patients,
incorporating the main organs for 18F-FDG absorption rates. The organs were located within the body using CT and
ultrasound images, while the body was constructed using anthropometric information from the Latin American population
as a reference. The absorption of 18F-FDG in each organ was determined during PET/CT exploration of the entire body.
The number of photons emitted by the organs was calculated using their respective metabolic absorption rate values. The
absorbed dose was estimated using Monte Carlo N-particle (MCNP) for three different activities: 6.6 mCi, 11 mCi, and 13
mCi, to compare the results with previously reported research. The tissues that absorbed the largest doses were the brain,
heart, and bladder. The absorbed dose in the brain was 14.34 mGy, 23.90 mGy, and 26.07 mGy, respectively. In the heart,
it was 14.97 mGy, 24.95 mGy, and 27.22 mGy, respectively. The bladder, on the other hand, was the organ that presented
the largest absorbed dose, with 24.62 mGy, 41.03 mGy, and 44.76 mGy, respectively. The other organs studied: the eye
lens, gonads, lungs, kidneys, thyroid, and uterus, showed an average dose much lower, approximately 5 mGy.
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