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Effect of Calculation Grid Size on Plan Calculation for Anisotropic Analytical Algorithm and Acuros XB Algorithm in lung Stereotactic Body Radiotherapy |
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PP: 1-5 |
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doi:10.18576/jrna/070301
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Author(s) |
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Ahmed Ali,
A. Hussein,
Mohmmed Galal,
Khaled El Shahat,
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Abstract |
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| : Background: The study aimed to determine the dose differences between Acuros XB (AXB) and Anisotropic Analytical Algorithm (AAA) in stereotactic body radiotherapy (SBRT) treatment for lung cancer and to investigate the dose-related effect of dose calculation grid size (CGS).
Methods. SBRT treatment was planned produced from the CT scan data of 15 patients suffering from stage I lung cancer, Clinically acceptable treatment plans with AAA were recalculated using AXB with the same monitor units (MU) and identical multileaf collimator (MLC) settings, using 1-mm and 2-mm and 3-mm CGS in the two algorithms to investigate their dosimetric affect. The Dose to planning target volumes (PTV) and organs at risk (OARs) between the two algorithms were compared. AAA and AXB algorithms with 6 MV flattening filter free (FFF) rays in Varian Trubeam STx.
Results: The dose to PTV predicted when AAA 1-mm CGS plans and AAA 2-mm and 3-mm CGS plans were compared, 2.73±1.62 % difference was observed; When AXB 1-mm CGS plans and AXB 2-mm and 3-mm CGS plans were compared, 1.36±1.21 % difference was found. No significant difference was found between plans with AAA 1-mm CGS and plans with AXB 1-mm CGS (p>0.05). On the other hand, there was a significant difference between plans with AAA 2, 3-mm and plans with AXB 2, 3-mm CGS (p<0.05).
Conclusion: As a result of the study, it was seen that the dose prediction for AXB algorithm are more stable results than the AAA in different intensity body regions, AXB principally predicts lower dose to PTV compared to AAA and the CGS contributes to the relative dose difference between the two algorithms. For SBRT, 1-mm CGS should be selected for calculation accuracy.
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