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Release Timing of Thyroid’s Carcinoma Patients from the Hospital after Radiodine (I-131) Therapy based on Dose rate Measurements |
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PP: 151-154 |
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doi:10.18576/jrna/060208
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Author(s) |
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M.S. El-Sayed Mansour,
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Abstract |
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| The therapeutic treatment of thyroid cancer generally comprises total or hemisphere thyroidectomy and oral administration of radioactive iodine (131I). One consideration in this therapy is the radiation exposure dangers, which have been leeding to the Regulatory Authority to guide line criteria on releasing patients from hospitals when the therapy procedure involves 131I activities as greater than 0.91GBq (30mCi). This study was administered to assess the time dependent rate following the administration of 131I activities and estimate the radioiodine effective half-life (Teff) inside the patient’s body, which would be useful for releasing patients from hospitals and guide radiation protection recommendations also . Patients were divided into two groups the ablation group (A) and the follow up group (FU). Furthermore, Dose rate, was measured at 1.0 meter. Per administrated Activities was 3700MBq, (100mCi). Patients were measured post 2h after 131I administration and at 24hour intervals up to 96hours. The results demonstrated a bi-exponential radioiodine clearance pattern up to five days with effective half-life Teff values of 15.9 and 25.3hours within the two phase, respectively. Also, majority of the patients follow up could be released from the hospital after 72 hours post-therapy administration as they reach the dose rate limit recommended by the regulatory authority by this time. |
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